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Article

Intranasal vaccination with an adjuvanted Norwalk virus-like particle vaccine elicits antigen-specific B memory responses in human adult volunteers.

Clinical immunology (Orlando, Fla.) - 1 Aug 2012

Ramirez Karina, Wahid Rezwanul, Richardson Charles, Bargatze Robert F, El-Kamary Samer S, Sztein Marcelo B, Pasetti Marcela F

Abstract excerpt

Noroviruses are the most frequent cause of acute gastroenteritis in humans of all ages. No vaccines are currently available. An intranasally delivered Norwalk (NV) virus-like particle (VLP) vaccine was recently shown to be well tolerated, immunogenic and to protect against infection in Phase 1 studies. Here, we examined B memory (B(M)) responses in volunteers who received the highest dosage levels of the NV-VLP...

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Identifiers

PMID: 22710446
DOI: 10.1016/j.clim.2012.05.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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