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Article

The Neurospora crassa dfg5 and dcw1 genes encode α-1,6-mannanases that function in the incorporation of glycoproteins into the cell wall.

PloS one - 1 Jan 2012

Maddi Abhiram, Fu Ci, Free Stephen J

Abstract excerpt

The covalent cross-linking of cell wall proteins into the cell wall glucan/chitin matrix is an important step in the biogenesis of the fungal cell wall. We demonstrate that the Neurospora crassa DFG5 (NCU03770) and DCW1 (NCU08127) enzymes function in vivo to cross-link glycoproteins into the cell wall. Mutants lacking DFG5 or DCW1 release slightly elevated levels of cell wall proteins into their growth medium....

Topics

Blotting, Western
Cell Wall
Chitin
Chromatography, Liquid
Cloning, Molecular
Galactose
Genes, Fungal
Glucans
Mannans
Mannosidases
Membrane Glycoproteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Models, Biological

Mutation

Neurospora crassa

Rosaniline Dyes

Tandem Mass Spectrometry

Source

Open in PubMed Open full text

Identifiers

PMID: 22701726
DOI: 10.1371/journal.pone.0038872
PMCID: PMC3372484

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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The Neurospora crassa dfg5 and dcw1 genes encode α-1,6-mannanases that function in the incorporation of glycoproteins into the cell wall.PMID 22701726Read ↗

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