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Article

Rapid whole-genome sequencing for investigation of a neonatal MRSA outbreak.

The New England journal of medicine - 14 Jun 2012

Köser Claudio U, Holden Matthew T G, Ellington Matthew J, Cartwright Edward J P, Brown Nicholas M, Ogilvy-Stuart Amanda L, Hsu Li Yang, Chewapreecha Claire, Croucher Nicholas J, Harris Simon R, Sanders Mandy, Enright Mark C, Dougan Gordon, Bentley Stephen D, Parkhill Julian, Fraser Louise J, Betley Jason R, Schulz-Trieglaff Ole B, Smith Geoffrey P, Peacock Sharon J

Abstract excerpt

BACKGROUND: Isolates of methicillin-resistant Staphylococcus aureus (MRSA) belonging to a single lineage are often indistinguishable by means of current typing techniques. Whole-genome sequencing may provide improved resolution to define transmission pathways and characterize outbreaks. METHODS: We investigated a putative MRSA outbreak in a neonatal intensive care unit. By using rapid high-throughput sequencing...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22693998
DOI: 10.1056/NEJMoa1109910
PMCID: PMC3715836

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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