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Article

Mast cell infiltration discriminates between histopathological phenotypes of chronic obstructive pulmonary disease.

American journal of respiratory and critical care medicine - 1 Aug 2012

Ballarin Andrea, Bazzan Erica, Zenteno Rafael Hernandez, Turato Graziella, Baraldo Simonetta, Zanovello Dora, Mutti Elena, Hogg James C, Saetta Marina, Cosio Manuel G

Abstract excerpt

RATIONALE: COPD is a complex disease with heterogeneous manifestations. Attempts have been made to define different phenotypes that could guide toward better disease understanding. We described before that smokers can develop either panlobular (PLE) or centrilobular emphysema (CLE). The latter has worse small airways remodeling and narrowing, which account for the airflow obstruction similar to asthma....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22679009
DOI: 10.1164/rccm.201112-2142OC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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