Article
An urgent need for a change in policy revealed by a study on prenatal testing for Duchenne muscular dystrophy.
European journal of human genetics : EJHG - 1 Jan 2013
Helderman-van den Enden Apollonia T J M, Madan Kamlesh, Breuning Martijn H, van der Hout Annemieke H, Bakker Egbert, de Die-Smulders Christine E M, Ginjaar Hendrika B
Abstract excerpt
Prenatal diagnosis for Duchenne muscular dystrophy (DMD) was introduced in the Netherlands in 1984. We have investigated the impact of 26 years (1984-2009) of prenatal testing. Of the 635 prenatal diagnoses, 51% were males; nearly half (46%) of these were affected or had an increased risk of DMD. As a result 145 male fetuses were aborted and 174 unaffected boys were born. The vast majority (78%) of females, now...
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