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Article

Impact of obesity on the bioavailability of peginterferon-α2a and ribavirin and treatment outcome for chronic hepatitis C genotype 2 or 3.

PloS one - 1 Jan 2012

Alsiö Åsa, Rembeck Karolina, Askarieh Galia, Christensen Peer Brehm, Färkkilä Martti, Langeland Nina, Buhl Mads Rauning, Pedersen Court, Mørch Kristine, Haagmans Bart L, Nasic Salmir, Westin Johan, Hellstrand Kristoffer, Norkrans Gunnar, Lagging Martin

Abstract excerpt

BACKGROUND AND AIMS: Having a body mass index above or equal to 30 kg/m(2) in conjunction with chronic hepatitis C virus infection is associated with non-responsiveness to treatment with interferon and ribavirin, but details regarding the mechanisms whereby obesity reduces the efficacy of therapy...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22655053
DOI: 10.1371/journal.pone.0037521
PMCID: PMC3360051

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Prepared record publication-22655053-2026-09-05.1. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 5 Sept 2026.

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