Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A molecular signature in blood identifies early Parkinson's disease.

Molecular neurodegeneration - 31 May 2012

Molochnikov Leonid, Rabey Jose M, Dobronevsky Evgenya, Bonucelli Ubaldo, Ceravolo Roberto, Frosini Daniela, Grünblatt Edna, Riederer Peter, Jacob Christian, Aharon-Peretz Judith, Bashenko Yulia, Youdim Moussa B H, Mandel Silvia A

Abstract excerpt

BACKGROUND: The search for biomarkers in Parkinson's disease (PD) is crucial to identify the disease early and monitor the effectiveness of neuroprotective therapies. We aim to assess whether a gene signature could be detected in blood from early/mild PD patients that could support the diagnosis of early PD, focusing on genes found particularly altered in the substantia nigra of sporadic PD. RESULTS: The...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Alzheimer Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Biomarkers

Share to Gene Expression

Share to Genetic Markers

Share to Parkinson Disease

Share to Predictive Value of Tests

Share to Sensitivity and Specificity

Source

Open in PubMed Open full text

Identifiers

PMID: 22651796
DOI: 10.1186/1750-1326-7-26
PMCID: PMC3424147

Genes

PSMC4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A molecular signature in blood identifies early Parkinson's disease.PMID 22651796Read ↗

Molecular markers of early Parkinson's disease based on gene expression in bloodSemantic proximity Read ↗

Found in transcription: Accurate Parkinson's disease classification in peripheral bloodSemantic proximity Read ↗

Identification of Blood-based Biomarkers for Early Stage Parkinson’s DiseaseSemantic proximity Read ↗

Analysis of blood-based gene expression in idiopathic Parkinson diseaseSemantic proximity Read ↗

Blood transcriptomics of drug-naïve sporadic Parkinson’s disease patientsSemantic proximity Read ↗

Gene Expression Differences in Peripheral Blood of Parkinson’s Disease Patients with Distinct Progression ProfilesSemantic proximity Read ↗

Leveraging blood RNA expression to understand Parkinson’s disease heterogeneity and progressionSemantic proximity Read ↗

Identification of biomarkers associated with Parkinson’s disease by gene expression profiling studies and bioinformatics analysisSemantic proximity Read ↗

Identification of a possible proteomic biomarker in Parkinson’s disease: discovery and replication in blood, brain and cerebrospinal fluidSemantic proximity Read ↗

A systems biology approach towards the identification of candidate therapeutic genes and potential biomarkers for Parkinson’s diseaseSemantic proximity Read ↗

A Machine Learning Approach to Parkinson’s Disease Blood TranscriptomicsSemantic proximity Read ↗

Identification of a novel proteomic Biomarker in Parkinson’s Disease: Discovery and Replication in Blood, brain and CSFSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.