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Article

Cell cycle commitment in budding yeast emerges from the cooperation of multiple bistable switches.

Open biology - 1 Nov 2011

Zhang Tongli, Schmierer Bernhard, Novák Béla

Abstract excerpt

The start-transition (START) in the G1 phase marks the point in the cell cycle at which a yeast cell initiates a new round of cell division. Once made, this decision is irreversible and the cell is committed to progressing through the entire cell cycle, irrespective of arrest signals such as pheromone. How commitment emerges from the underlying molecular interaction network is poorly understood. Here, we perform...

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Identifiers

PMID: 22645649
DOI: 10.1098/rsob.110009
PMCID: PMC3352082

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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