Article
The hdhA gene encodes a haloacid dehalogenase that is regulated by the LysR-type regulator, HdhR, in Sinorhizobium meliloti.
Molecular biotechnology - 1 Jun 2013
Sallabhan Ratiboot, Kerdwong Jarunee, Dubbs James M, Somsongkul Kumpanart, Whangsuk Wirongrong, Piewtongon Phairin, Mongkolsuk Skorn, Loprasert Suvit
Abstract excerpt
The plasmid pSymA, in the nitrogen-fixing soil bacterium, Sinorhizobium meliloti, carries a 750-bp ORF (SMa1978) designated, hdhA, which encodes a novel dehalogenase that can detoxify haloacid compounds, showing a preference for haloacetic acids. Purified His-tagged HdhA demonstrated the apparent ability to dehalogenate chloroacetic acid and trifluoroacetic acid. In addition, upstream of hdhA, a gene encoding a...
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