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Article

The inclusion of an assay for inherited congenital malformations in the assessment of mutagenicity.

Mutagenesis - 1 Sept 1990

Douglas G R

Abstract excerpt

A number of national guidelines and regulations on the mutagenicity of chemical substances mandate the assessment of inherited genetic effects. While inherited congenital malformations represent a major component of genetically-based adverse human health effects, tests for such effects are not used by regulatory agencies to evaluate inherited genetic effects. This paper is intended to highlight some of the...

Topics

Abnormalities, Drug-Induced
Abnormalities, Radiation-Induced
Animals
Chromosome Aberrations
Humans
Mutagenicity Tests
Mutation

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 2263199
DOI: 10.1093/mutage/5.5.421

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2263199-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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