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Article

Surf the Post-translational Modification Network of p53 Regulation

1 Jan 2012

Abstract excerpt

Among the human genome, p53 is one of the first tumor suppressor genes to be discovered. It has a wide range of functions covering cell cycle control, apoptosis, genome integrity maintenance, metabolism, fertility, cellular reprogramming and autophagy. Although different possible underlying mechanisms for p53 regulation have been proposed for decades, none of them is conclusive. While much literature focuses on...

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PMID: 22606048
DOI: 10.7150/ijbs.4283

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