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Article

Positive and negative transcriptional regulatory elements in the early H4 histone gene of the sea urchin, Strongylocentrotus purpuratus.

Nucleic acids research - 25 Dec 1990

Tung L, Lee I J, Rice H L, Weinberg E S

Abstract excerpt

The early H4 (EH4) histone gene of the sea urchin, Strongylocentrotus purpuratus, is shown to contain at least five positive-responding sequence elements and one negative-responding site which control the level of in vitro transcription in an embryonic nuclear extract. The positive acting element...

Topics

Animals
Base Sequence
Chromosome Deletion
Gene Expression Regulation
Genes
Genes, Regulator
Histones
Molecular Sequence Data
Mutation
Promoter Regions, Genetic
Regulatory Sequences, Nucleic Acid
Sea Urchins

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Transcription, Genetic

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Identifiers

PMID: 2259627
DOI: 10.1093/nar/18.24.7339
PMCID: PMC332871

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2259627-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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