Article
Creation of cis-regulatory elements during sea urchin evolution by co-option and optimization of a repetitive sequence adjacent to the spec2a gene.
Developmental biology - 15 Sept 2004
Dayal Sandeep, Kiyama Takae, Villinski Jeffrey T, Zhang Ning, Liang Shuguang, Klein William H
Abstract excerpt
The creation, preservation, and degeneration of cis-regulatory elements controlling developmental gene expression are fundamental genome-level evolutionary processes about which little is known. Here, we identify critical differences in cis-regulatory elements controlling the expression of the sea urchin aboral ectoderm-specific spec genes. We found multiple copies of a repetitive sequence element termed RSR in...
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