Article
ERK1/2 regulate exocytosis through direct phosphorylation of the exocyst component Exo70.
Developmental cell - 15 May 2012
Ren Jinqi, Guo Wei
Abstract excerpt
The exocyst is a multiprotein complex essential for exocytosis and plasma membrane remodeling. The assembly of the exocyst complex mediates the tethering of post-Golgi secretory vesicles to the plasma membrane prior to fusion. Elucidating the mechanisms regulating exocyst assembly is important for the understanding of exocytosis. Here we show that the exocyst component Exo70 is a direct substrate of the...
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