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Article

A group of atopic dermatitis without IgE elevation or barrier impairment shows a high Th1 frequency: possible immunological state of the intrinsic type.

Journal of dermatological science - 1 Jul 2012

Kabashima-Kubo Rieko, Nakamura Motonobu, Sakabe Jun-ichi, Sugita Kazunari, Hino Ryosuke, Mori Tomoko, Kobayashi Miwa, Bito Toshinori, Kabashima Kenji, Ogasawara Koetsu, Nomura Yukiko, Nomura Toshifumi, Akiyama Masashi, Shimizu Hiroshi, Tokura Yoshiki

Abstract excerpt

BACKGROUND: Atopic dermatitis (AD) can be classified into the major extrinsic type with high serum IgE levels and impaired barrier, and the minor intrinsic type with normal IgE levels and unimpaired barrier. OBJECTIVE: To characterize the intrinsic type of Japanese AD patients in the T helper cel...

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Identifiers

PMID: 22591815
DOI: 10.1016/j.jdermsci.2012.04.004

Genes

CCL17
FLG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22591815-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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