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Using Germline Genomics to Individualize Pediatric Cancer Treatments

14 May 2012

Abstract excerpt

The amazing successes in cure rates for children with cancer over the last century have come in large part from identifying clinical, genetic, and molecular variables associated with response to therapy in large cooperative clinical trials and stratifying therapies according to the predicted risk of relapse. There is an expanding interest in identifying germline genomic variants, as opposed to genetic variants...

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PMID: 22589487
DOI: 10.1158/1078-0432.ccr-11-1938

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