Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Over-representation of the G12S polymorphism of the SDHD gene in patients with MEN2A syndrome.

Clinics (Sao Paulo, Brazil) - 1 Jan 2012

Lendvai Nikoletta, Tóth Miklos, Valkusz Zsuzsanna, Bekő Gabriella, Szücs Nikolette, Csajbók Eva, Igaz Péter, Kriszt Balázs, Kovács Balázs, Rácz Károly, Patócs Attila

Abstract excerpt

OBJECTIVE: To evaluate whether germline variants of the succinate dehydrogenase genes might be phenotypic modifiers in patients with multiple endocrine neoplasia type 2. Mutations of genes encoding subunits of the succinate dehydrogenase are associated with hereditary paraganglioma/pheochromocytoma syndrome. Pheochromocytoma is one of the main manifestations of multiple endocrine neoplasia type 2 caused by...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Calcitonin
Share to Carcinoma, Neuroendocrine

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Multiple Endocrine Neoplasia Type 2a

Share to Pheochromocytoma

Share to Proto-Oncogene Mas

Share to Proto-Oncogene Proteins c-ret

Share to Succinate Dehydrogenase

Share to Thyroid Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 22584711
DOI: 10.6061/clinics/2012(sup01)15
PMCID: PMC3328831

Genes

SDHD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Over-representation of the G12S polymorphism of the SDHD gene in patients with MEN2A syndrome.PMID 22584711Read ↗

Germline DLST Variants Promote Epigenetic Modifications in Pheochromocytoma-Paraganglioma.Semantic proximity Read ↗

Epigenetic Mutation of the Succinate Dehydrogenase C Promoter in a Patient With Two Paragangliomas.Semantic proximity Read ↗

Succinate Dehydrogenase (SDH) D Subunit (SDHD) Inactivation in a Growth-Hormone-Producing Pituitary Tumor: A New Association for SDH?Semantic proximity Read ↗

SDH mutations establish a hypermethylator phenotype in paraganglioma.Semantic proximity Read ↗

Succinate dehydrogenase (SDHx) mutations in pituitary tumors: could this be a new role for mitochondrial complex II and/or Krebs cycle defects?Semantic proximity Read ↗

High prevalence of founder mutations of the succinate dehydrogenase genes in the Netherlands.Semantic proximity Read ↗

Mitochondrial complex II and genomic imprinting in inheritance of paraganglioma tumors.Semantic proximity Read ↗

Molecular analysis of pheochromocytoma after maternal transmission of SDHD mutation elucidates mechanism of parent-of-origin effect.Semantic proximity Read ↗

Disomy as the genetic underlying mechanisms of loss of heterozigosity in SDHD-paragangliomas.Semantic proximity Read ↗

A recurrent stop-codon mutation in succinate dehydrogenase subunit B gene in normal peripheral blood and childhood T-cell acute leukemia.Semantic proximity Read ↗

Inhibition of succinate dehydrogenase dysregulates histone modification in mammalian cellsSemantic proximity Read ↗

Predominant expression of mutated allele of the succunate dehydrogenase D (SDHD) gene in the SDHD-related paragangliomas.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.