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p53 Activation following Rift Valley Fever Virus Infection Contributes to Cell Death and Viral Production

4 May 2012

Abstract excerpt

Rift Valley fever virus (RVFV) is an emerging viral zoonosis that is responsible for devastating outbreaks among livestock and is capable of causing potentially fatal disease in humans. Studies have shown that upon infection, certain viruses have the capability of utilizing particular cellular signaling pathways to propagate viral infection. Activation of p53 is important for the DNA damage signaling cascade,...

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PMID: 22574148
DOI: 10.1371/journal.pone.0036327

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