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Article

Macroautophagy in T Lymphocyte Development and Function

1 Jan 2012

Abstract excerpt

Macroautophagy (referred to as autophagy) is a fundamental intracellular process characterized by the sequestration of cytoplasmic compartments through double-membrane vesicles, termed autophagosomes. Recent studies have established important roles of autophagy in regulating T lymphocyte development and function. Resting T lymphocytes have basal levels of autophagy that is upregulated by T cell receptor...

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PMID: 22566906
DOI: 10.3389/fimmu.2012.00022

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