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Models of in vitro spermatogenesis

1 Jan 2012

Abstract excerpt

Understanding the mechanisms that lead to the differentiation of male germ cells from their spermatogonial stem cells through meiosis to give rise to mature haploid spermatozoa has been a major quest for many decades. Unlike most other cell types this differentiation process is more or less completely dependent upon the cells being located within the strongly structured niche provided by mature Sertoli cells...

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PMID: 22553488
DOI: 10.4161/spmg.19383

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