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Article

Ontogeny of Lafora bodies and neurocytoskeleton changes in Laforin-deficient mice.

Experimental neurology - 1 Jul 2012

Machado-Salas Jesús, Avila-Costa María Rosa, Guevara Patricia, Guevara Jorge, Durón Reyna M, Bai Dongsheng, Tanaka Miyabi, Yamakawa Kazuhiro, Delgado-Escueta Antonio V

Abstract excerpt

Lafora disease (LD) is an autosomal recessive, always fatal progressive myoclonus epilepsy with rapid cognitive and neurologic deterioration. One of the pathological hallmarks of LD is the presence of cytoplasmic PAS+polyglucosan inclusions called Lafora bodies (LBs). Current clinical and neuropathological views consider LBs to be the cause of neurological derangement of patients. A systematic study of the...

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Identifiers

PMID: 22542948
DOI: 10.1016/j.expneurol.2012.04.008
PMCID: PMC3367664

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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