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Article

Use of matrix-assisted laser desorption ionization-time of flight mass spectrometry for caspofungin susceptibility testing of Candida and Aspergillus species.

Journal of clinical microbiology - 1 Jul 2012

De Carolis Elena, Vella Antonietta, Florio Ada R, Posteraro Patrizia, Perlin David S, Sanguinetti Maurizio, Posteraro Brunella

Abstract excerpt

Matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) was evaluated for testing susceptibility to caspofungin of wild-type and fks mutant isolates of Candida and Aspergillus. Complete essential agreement was observed with the CLSI reference method, with categorical agreement for 94.1% of the Candida isolates tested. Thus, MALDI-TOF MS is a reliable and accurate method to...

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Identifiers

PMID: 22535984
DOI: 10.1128/JCM.00224-12
PMCID: PMC3405623

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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