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Article

Integrated epigenomics identifies <i>BMP4</i> as a modulator of cisplatin sensitivity in gastric cancer

25 Apr 2012

Abstract excerpt

OBJECTIVE: Cisplatin is a widely used gastric cancer (GC) chemotherapy; however, genetic factors regulating GC responses to cisplatin remain obscure. Identifying genes regulating cisplatin resistance could aid clinicians in tailoring treatments, by distinguishing cisplatin sensitive patients from those who might benefit from alternative platinum therapies, and highlight novel targeted strategies for overcoming...

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PMID: 22535375
DOI: 10.1136/gutjnl-2011-301113

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