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Molecular-Phylogenetic Characterization of the Microbiota in Ulcerated and Non-Ulcerated Regions in the Patients with Crohn's Disease

18 Apr 2012

Abstract excerpt

BACKGROUND: The dysbiosis of intestinal microbiota has been established in Crohn's disease (CD), but the molecular characterization of this dysbiosis in Chinese subjects with CD remains unclear. This study aims to investigate the predominant bacterial composition of the faecal and mucosal-associated microbiota in Chinese CD patients using culture-independent techniques. METHODS/PRINCIPAL FINDINGS: Eighteen...

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PMID: 22529960
DOI: 10.1371/journal.pone.0034939

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