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Abnormal microbiota composition in the ileocolonic mucosa of Crohnʼs disease patients as revealed by polymerase chain reaction-denaturing gradient gel electrophoresis

18 Nov 2006

Abstract excerpt

BACKGROUND: Bacteria might play a role in the pathogenesis of Crohn's disease (CD), and patients harbor a different type and density of gut microbiota compared with normal healthy subjects. Thus, the aim of this study was to compare the microbiota adhered to the mucosa of CD patients with that of healthy subjects. METHODS: Polymerase chain reaction-denaturing gradient gel electrophoresis (PCR-DGGE) of 16S rRNA...

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PMID: 17119388
DOI: 10.1097/01.mib.0000235828.09305.0c

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