Article
[Glucokinase gene mutation as a causative factor of permanent neonatal diabetes mellitus].
Pediatric endocrinology, diabetes, and metabolism - 1 Jan 2012
Wajda-Cuszlag Małgorzata, Witkowski Daniel, Piontek Elżbieta, Wysocka-Mincewicz Marta, Borowiec Maciej, Młynarski Wojciech, Szalecki Mieczysław
Abstract excerpt
INTRODUCTION: The most frequent type of diabetes in childhood is type 1 diabetes. Thanks to the development of genetic testing, the rare monogenic forms of that disease have been defined. One of them is neonatal diabetes identified within the first 6 months of life and often associated with the mutation in KCNJ11, ABCC8 or insulin gene. A less frequent mutation in the glucokinase gene can cause both permanent...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.