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Article

[From gene to disease; neonatal diabetes mellitus and the KCNJ11 gene].

Nederlands tijdschrift voor geneeskunde - 3 Dec 2005

Slingerland A S, Bruining G J

Abstract excerpt

Neonatal diabetes mellitus (DM) is by definition diagnosed within the first 3 months of life and can be either transient (TNDM) or permanent (PNDM). Recently, activating mutations in the KCNJ11 gene, which encodes the Kir6.2 subunit of the K(ATP) channel, have been identified as a cause of TNDM, the main cause of PNDM, and the cause of a new syndrome: developmental delay, epilepsy and neonatal diabetes. Patients...

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Share to Diabetes Mellitus, Type 1
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Infant, Newborn

Share to Insulin

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Share to Potassium Channels, Inwardly Rectifying

Source

Identifiers

PMID: 16375017

Genes

KCNJ11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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[From gene to disease; neonatal diabetes mellitus and the KCNJ11 gene].PMID 16375017Read ↗

[Neonatal diabetes mellitus].Semantic proximity Read ↗

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Activating mutations in Kir6.2 and neonatal diabetes: new clinical syndromes, new scientific insights, and new therapy.Semantic proximity Read ↗

Neonatal diabetes: an expanding list of genes allows for improved diagnosis and treatment.Semantic proximity Read ↗

Mutations in the Kir6.2 subunit of the KATP channel and permanent neonatal diabetes: new insights and new treatment.Semantic proximity Read ↗

Molecular Basis of Neonatal Diabetes Mellitus and Transient Hyperglycemia in the NeonateSemantic proximity Read ↗

[Neonatal diabetes mellitus].Semantic proximity Read ↗

Kir6.2 Mutations Are a Common Cause of Permanent Neonatal Diabetes in a Large Cohort of French PatientsSemantic proximity Read ↗

Permanent neonatal diabetes due to activating mutations in ABCC8 and KCNJ11.Semantic proximity Read ↗

KATP Channel Mutations and Neonatal Diabetes.Semantic proximity Read ↗

Mutations in KCNJ11, which encodes Kir6.2, are a common cause of diabetes diagnosed in the first 6 months of life, with the phenotype determined by genotype.Semantic proximity Read ↗

[Neonatal diabetes: a disease linked to multiple mechanisms].Semantic proximity Read ↗

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