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Article

Inflammasome polymorphisms confer susceptibility to sporadic malignant melanoma.

Pigment cell & melanoma research - 1 Jul 2012

Verma Deepti, Bivik Cecilia, Farahani Ensieh, Synnerstad Ingrid, Fredrikson Mats, Enerbäck Charlotta, Rosdahl Inger, Söderkvist Peter

Abstract excerpt

Genetic variants of NLRP3 and NLRP1 are known to modulate levels of pro-inflammatory cytokine interleukin (IL)-1β. The purpose of this study was to investigate the association of NLRP3/NLRP1 polymorphisms with susceptibility and clinical features of malignant melanoma in a Swedish case-control study. Common variants in NLRP3/NLRP1 were investigated in sporadic malignant melanoma patients and healthy controls...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22524199
DOI: 10.1111/j.1755-148X.2012.01008.x

Genes

NLRP1
NLRP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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