Article
The molecular characterisation of unusual subcutaneous spindle cell lesion of breast.
Journal of clinical pathology - 1 Aug 2012
Takano Elena A, Rogers Toni-Maree, Young Richard J, Rayoo Mukta, Kostos Phillip, Ferguson Ross, Campbell Ian G, Debiec-Rychter Maria, Fox Stephen B
Abstract excerpt
BACKGROUND: Spindle cell lesions of the breast represent an interesting diagnostic challenge as they comprise a wide range of tumours that are rare. Differentiating dermatofibrosarcoma protuberans (DFSP) from other dermatofibromas using CD34 immunohistochemistry alone is difficult; therefore, fluorescence in situ hybridisation (FISH) analysis is often employed to identify typical COL1A1-PDGFB fusion or gene...
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