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Renal Cell Carcinoma Associated With Transcription Factor E3 Expression and Xp11.2 Translocation

20 Apr 2012

Abstract excerpt

We studied the characteristics and prognosis of renal cell carcinoma (RCC) associated with Xp11.2 translocation and transcription factor E3 (TFE3) expression and determined the need for genetic analysis in routine diagnostics. Of 848 consecutive cases, 75 showed microscopic features suggestive of Xp11.2 translocation RCC or occurred in patients 40 years or younger. Of these cases, 17 (23%) showed strong nuclear...

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PMID: 22523215
DOI: 10.1309/ajcpq6llfmc4oxgc

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