Article
Association between kinase insert domain-containing receptor gene polymorphisms and silent brain infarction: a Korean study.
Journal of the neurological sciences - 15 Jul 2012
Han In-Bo, Kim Ok-Joon, Ropper Alexander E, Kim Hyun-Seok, Cho Yun-Kyung, Teng Yang D, Kim Nam-Keun
Abstract excerpt
BACKGROUND: Kinase insert domain-containing receptor (KDR), vascular endothelial growth factor receptor-2, play a pivotal role in endothelial dysfunction, which may lead to silent brain infarction (SBI). We evaluated whether single nucleotide polymorphisms (SNPs) of KDR genes are associated with increased risk of SBI in a Korean population. METHODS: A total of 383 patients with SBI and 387 controls were genotyped...
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