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Article

High efficacy of adefovir and entecavir combination therapy in patients with nucleoside-refractory hepatitis B.

The Korean journal of hepatology - 1 Mar 2012

Chae Hee Bok, Kim Mee Jin, Seo Eui Geun, Choi Yong Hyeok, Lee Hee Seung, Han Joung Ho, Yoon Soon Man, Park Seon Mee, Youn Sei Jin

Abstract excerpt

BACKGROUND/AIMS: Newly developed and potent antiviral agents suffer from the problem of drug resistance. Multidrug resistance is a major impediment in the treatment of patients with chronic hepatitis B (CHB). In line with American Association for the Study of Liver Diseases guidelines, adefovir dipivoxil (ADV) add-on therapy is recommended in the case of lamivudine resistance, while tenofovir disoproxil fumarate...

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Identifiers

PMID: 22511906
DOI: 10.3350/kjhep.2012.18.1.75
PMCID: PMC3326991

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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