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Article

Susceptibility variants for obesity and colorectal cancer risk: the multiethnic cohort and PAGE studies.

International journal of cancer - 15 Sept 2012

Lim Unhee, Wilkens Lynne R, Monroe Kristine R, Caberto Christian, Tiirikainen Maarit, Cheng Iona, Park Sungshim Lani, Stram Daniel O, Henderson Brian E, Kolonel Laurence N, Haiman Christopher A, Le Marchand Loïc

Abstract excerpt

Obesity is a leading contributor to colorectal cancer risk. We investigated whether the risk variants identified in genome-wide association studies of body mass index (BMI) and waist size are associated with colorectal cancer risk, independently of the effect of obesity phenotype due to a shared etiology. Twenty-four single nucleotide polymorphisms (SNPs) in 15 loci (BDNF, FAIM2, FTO, GNPDA2, KCTD15, LYPLAL1,...

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Share to Alpha-Ketoglutarate-Dependent Dioxygenase FTO
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22511254
DOI: 10.1002/ijc.27592
PMCID: PMC3402643

Genes

KCTD15
BDNF
FAIM2
FTO
GNPDA2
LYPLAL1
MSRA
MTCH2
NEGR1
NRXN3
TMEM18

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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