Article
HLA-targeted cell sorting of microchimeric cells opens the way to phenotypical and functional characterization.
Chimerism - 1 Jan 2000
Eikmans Michael, Claas Frans H J
Abstract excerpt
Microchimerism refers to the presence of less than 1% of non-host cells in a person. Our group developed a reliable method for separating viable microchimeric cells from the host environment. Optimal separation of microchimeric cells at proportions as low as 0.01% could be established with two monoclonal antibodies directed against different HLA antigens, one targeting the microchimeric cells and the other the...
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