Article
Cleavage and Structural Transitions during Maturation of Staphylococcus aureus Bacteriophage 80α and SaPI1 Capsids.
Viruses - 16 Dec 2017
Kizziah James L, Manning Keith A, Dearborn Altaira D, Wall Erin A, Klenow Laura, Hill Rosanne L L, Spilman Michael S, Stagg Scott M, Christie Gail E, Dokland Terje
Abstract excerpt
In the tailed bacteriophages, DNA is packaged into spherical procapsids, leading to expansion into angular, thin-walled mature capsids. In many cases, this maturation is accompanied by cleavage of the major capsid protein (CP) and other capsid-associated proteins, including the scaffolding protein (SP) that serves as a chaperone for the assembly process. Staphylococcus aureus bacteriophage 80α is capable of high...
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