Article
CGG-repeat expansion in FMR1 is not associated with amyotrophic lateral sclerosis.
Neurobiology of aging - 1 Aug 2012
Groen Ewout J N, van Rheenen Wouter, Koppers Max, van Doormaal Perry T C, Vlam Lotte, Diekstra Frank P, Dooijes Dennis, Pasterkamp R Jeroen, van den Berg Leonard H, Veldink Jan H
Abstract excerpt
Recently, repeat expansions in several genes have been shown to cause or be associated with amyotrophic lateral sclerosis (ALS). It has been demonstrated that an intronic hexanucleotide repeat expansion in C9ORF72 is a major cause of both familial (approximately 40%) and sporadic (approximately 5%) ALS, as well as frontotemporal dementia (FTD). In addition, a CAG-repeat expansion in exon 1 of ATXN2, otherwise...
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