Article
Unhealthy diet and ultrafine carbon black particles induce senescence and disease associated phenotypic changes.
Experimental gerontology - 1 Jan 2013
Büchner Nicole, Ale-Agha Niloofar, Jakob Sascha, Sydlik Ulrich, Kunze Kerstin, Unfried Klaus, Altschmied Joachim, Haendeler Judith
Abstract excerpt
Diet and pollution are environmental factors known to compromise "healthy aging" of the cardiovascular and respiratory systems. The molecular consequences of this permanent burden in these cells are still unknown. Therefore, this study investigates the impact of unhealthy diet on aging-related signaling pathways of human, primary cardiovascular cells and of airborne particles on lung epithelial and human...
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