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Article

Longer leukocyte telomere length is associated with smaller hippocampal volume among non-demented APOE ε3/ε3 subjects.

PloS one - 1 Jan 2012

Wikgren Mikael, Karlsson Thomas, Lind Johanna, Nilbrink Therese, Hultdin Johan, Sleegers Kristel, Van Broeckhoven Christine, Roos Göran, Nilsson Lars-Göran, Nyberg Lars, Adolfsson Rolf, Norrback Karl-Fredrik

Abstract excerpt

Telomere length shortens with cellular division, and leukocyte telomere length is used as a marker for systemic telomere length. The hippocampus hosts adult neurogenesis and is an important structure for episodic memory, and carriers of the apolipoprotein E ε4 allele exhibit higher hippocampal atrophy rates and differing telomere dynamics compared with non-carriers. The authors investigated whether leukocyte...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22506016
DOI: 10.1371/journal.pone.0034292
PMCID: PMC3323621

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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