Article
New direct-acting antiviral agents for the treatment of hepatitis C virus infection and perspectives.
Gut - 1 May 2012
Welsch Christoph, Jesudian Arun, Zeuzem Stefan, Jacobson Ira
Abstract excerpt
Until recently, the standard of care (SOC) for patients with chronic hepatitis C virus (HCV) infection has consisted of a combination of pegylated interferon-α [corrected] plus ribavirin, administered for 24- to 48-weeks depending on the HCV genotype. The sustained virologic response rate for this SOC has been only about 50% in patients infected with genotype 1 HCV, the most prevalent genotype in Europe and North...
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