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Article

TFE3 Rearrangements in Adult Renal Cell Carcinoma

12 Apr 2012

Abstract excerpt

Renal cell carcinoma (RCC) with chromosomal rearrangement of transcription factor for immunoglobulin heavy-chain enhancer 3 (TFE3) at Xp11.2 is a distinct subtype that was initially described in children and has been reported to display an indolent course. Recent reports have identified RCC with TFE3 rearrangements in adults and have suggested a more aggressive course in this population. However, only a few...

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PMID: 22498819
DOI: 10.1097/pas.0b013e31824dd972

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