Article
Sequence analysis and HLA-DR genotyping of a novel HLA-DRw14 allele.
Immunogenetics - 1 Jan 1990
Obata F, Ito I, Ito K, Abe A, Ohkubo M, Onda K, Yang Y G, Watanabe K, Kashiwagi N
Abstract excerpt
Analysis of a Japanese population by oligonucleotide genotyping revealed that one Japanese HLA-DRw14 allele had a DRB1 genotype different from that of the known HLA-DRw14-related alleles, DRB1*1401 (DRw14-Dw9) and DRB1*1402 (DRw14-Dw16). The second exon of the DRB1 gene of the novel DRw14 allele (designated DRB1-14c) was amplified enzymatically and sequenced after cloning into a plasmid vector. The amino acid...
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