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Article

Mining and modeling human genetics for autism therapeutics.

Current opinion in neurobiology - 1 Oct 2012

Smith Daniel G, Ehlers Michael D

Abstract excerpt

A growing understanding of the genetic origins of autism spectrum disorders (ASDs) and the impact of ASD risk genes on synaptic function presents new opportunities for drug discovery. Large-scale human genetics studies have begun to reveal molecular pathways and potential therapeutic drug targets. Subsequent validation and characterization of ASD risk genes in mouse models holds promise for defining relevant...

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Identifiers

PMID: 22483267
DOI: 10.1016/j.conb.2012.03.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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