Article
Autism spectrum disorders: from genes to neurobiology.
Current opinion in neurobiology - 1 Feb 2015
Willsey A Jeremy, State Matthew W
Abstract excerpt
Advances in genome-wide technology, coupled with the availability of large cohorts, are finally yielding a steady stream of autism spectrum disorder (ASD) genes carrying mutations of large effect. These findings represent important molecular clues, but at the same time present notable challenges to traditional strategies for moving from genes to neurobiology. A remarkable degree of genetic heterogeneity, the...
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