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Article

Translating genetic and preclinical findings into autism therapies.

Dialogues in clinical neuroscience - 1 Dec 2017

Chahrour Maria, Kleiman Robin J, Manzini M Chiara

Abstract excerpt

Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder characterized by social deficits and repetitive/restrictive interests. ASD is associated with multiple comorbidities, including intellectual disability, anxiety, and epilepsy. Evidence that ASD is highly heritable has spurred major efforts to unravel its genetics, revealing possible contributions from hundreds of genes through rare and common...

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PMID: 29398929
PMCID: PMC5789211

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