Article
Recapitulation of genome-wide association studies on pulse pressure and mean arterial pressure in the Korean population.
Journal of human genetics - 1 Jun 2012
Hong Kyung-Won, Min Haesook, Heo Byeong-Mun, Joo Seong Eun, Kim Sung Soo, Kim Yeonjung
Abstract excerpt
Increased pulse pressure (PP) and decreased mean arterial pressure (MAP) are strong prognostic predictors of adverse cardiovascular events. Recently, the International Consortium for Blood Pressure Genome-Wide Association Studies (ICBP-GWAS) reported eight loci that influenced PP and MAP. The ICBP-GWAS examined 51 cohorts--comprising 122 671 individuals of European ancestry--and identified eight SNPs: five that...
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