Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Induction of Apoptosis Coupled to Endoplasmic Reticulum Stress in Human Prostate Cancer Cells by n-butylidenephthalide

28 Mar 2012

Abstract excerpt

BACKGROUND: N-butylidenephthalide (BP) exhibits antitumor effect in a variety of cancer cell lines. The objective of this study was to obtain additional insights into the mechanisms involved in BP induced cell death in human prostate cancer cells. METHODS/PRINCIPAL FINDINGS: Two human prostate cancer cell lines, PC-3 and LNCaP, were treated with BP, and subsequently evaluated for their viability and cell cycle...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer, Hypoxia, and Metabolism
Share to Neurological Disease Mechanisms and Treatments
Share to Traditional Chinese Medicine Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22470469
DOI: 10.1371/journal.pone.0033742

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Induction of Apoptosis Coupled to Endoplasmic Reticulum Stress in Human Prostate Cancer Cells by n-butylidenephthalidePMID 22470469Read ↗

Anethole Inhibits the Proliferation of Human Prostate Cancer Cells via Induction of Cell Cycle Arrest and ApoptosisSemantic proximity Read ↗

The unfolded protein response during prostate cancer developmentSemantic proximity Read ↗

Tunicamycin induced endoplasmic reticulum stress promotes apoptosis of prostate cancer cells by activating mTORC1Semantic proximity Read ↗

Procyanidin B2 3,3″-di-O-gallate, a Biologically Active Constituent of Grape Seed Extract, Induces Apoptosis in Human Prostate Cancer Cells Via Targeting NF-κB, Stat3, and AP1 Transcription FactorsSemantic proximity Read ↗

Oridonin induces growth inhibition and apoptosis of a variety of human cancer cellsSemantic proximity Read ↗

Emodin induced necroptosis in prostate cancer cells via the mitochondrial fission HSP90/MLKL/PGAM pathwaySemantic proximity Read ↗

Cyanidin induces apoptosis and differentiation in prostate cancer cellsSemantic proximity Read ↗

Combination Therapy with the Histone Deacetylase Inhibitor LBH589 and Radiation Is an Effective Regimen for Prostate Cancer CellsSemantic proximity Read ↗

Ionizing Radiation Induces Prostate Cancer Neuroendocrine Differentiation through Interplay of CREB and ATF2: Implications for Disease ProgressionSemantic proximity Read ↗

Molecular mechanisms for apigenin‐induced cell‐cycle arrest and apoptosis of hormone refractory human prostate carcinoma DU145 cellsSemantic proximity Read ↗

The involvement of cannabis sativa/CBD in prostate cancer pc3 cells progression inhibitionSemantic proximity Read ↗

2-methoxyestradiol blocks cell-cycle progression at G(2)/M phase and inhibits growth of human prostate cancer cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.