Article
Drug susceptibility of Mycobacterium tuberculosis Beijing genotype and association with MDR TB.
Emerging infectious diseases - 1 Apr 2012
de Steenwinkel Jurriaan E M, ten Kate Marian T, de Knegt Gerjo J, Kremer Kristin, Aarnoutse Rob E, Boeree Martin J, Verbrugh Henri A, van Soolingen Dick, Bakker-Woudenberg Irma A J M
Abstract excerpt
To determine differences in the ability of Mycobacterium tuberculosis strains to withstand antituberculosis drug treatment, we compared the activity of antituberculosis drugs against susceptible Beijing and East-African/Indian genotype M. tuberculosis strains. Beijing genotype strains showed high rates of mutation within a wide range of drug concentrations, possibly explaining this genotype's association with...
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