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Article

Identification of intermediate in evolutionary model of enterohemorrhagic Escherichia coli O157.

Emerging infectious diseases - 1 Apr 2012

Jenke Christian, Leopold Shana R, Weniger Thomas, Rothgänger Jörg, Harmsen Dag, Karch Helge, Mellmann Alexander

Abstract excerpt

Highly pathogenic enterohemorrhagic Escherichia coli (EHEC) O157 cause a spectrum of clinical signs that include diarrhea, bloody diarrhea, and hemolytic uremic syndrome. The current evolutionary model of EHEC O157:H7/H(-) consists of a stepwise evolution scenario proceeding from O55:H7 to a node (hypothetical intermediate) that then branches into sorbitol-fermenting (SF) O157:H(-) and non-SF (NSF) O157:H7. To...

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PMID: 22469031
DOI: 10.3201/eid1804.111414
PMCID: PMC3309690

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NSF

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