Article
Selfish cellular networks and the evolution of complex organisms.
Comptes rendus biologies - 1 Mar 2012
Kourilsky Philippe
Abstract excerpt
Human gametogenesis takes years and involves many cellular divisions, particularly in males. Consequently, gametogenesis provides the opportunity to acquire multiple de novo mutations. A significant portion of these is likely to impact the cellular networks linking genes, proteins, RNA and metabolites, which constitute the functional units of cells. A wealth of literature shows that these individual cellular...
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