Article
Genetic variation in vascular endothelial growth factor-a and lung function.
American journal of respiratory and critical care medicine - 1 Jun 2012
Simpson Angela, Custovic Adnan, Tepper Robert, Graves Penelope, Stern Debra A, Jones Marcus, Hankinson Jenny, Curtin John A, Wu Jiakai, Blekic Mario, Bukvic Blazenka Kljaic, Aberle Neda, Marinho Susana, Belgrave Danielle, Morgan Wayne J, Martinez Fernando D
Abstract excerpt
RATIONALE: Given the role of vascular endothelial growth factor (VEGF) in lung development, we hypothesized that polymorphisms in VEGF-A may be associated with lung function. OBJECTIVES: The current study was designed to assess the role of genetic variants in VEGF-A as determinants of airway function from infancy through early adulthood. METHODS: Association between five single-nucleotide polymorphisms (SNPs) in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.